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Formula Sheets / Chemistry

Chapter 29

Amines

Revise with flashcards Download this chapter (PDF) All Chemistry formulas (PDF)
Aliphatic and aromatic aminesDiazonium saltsCyanides, isocyanides and nitro compounds

Aliphatic and aromatic amines

  • Hoffmann bromamide

    RCONH2​+Br2​+4NaOH→RNH2​  (one carbon fewer)
  • Gabriel phthalimide

    gives 1∘ aliphatic amines only
  • Hinsberg test

    1∘: product dissolves in alkali;2∘: insoluble;3∘: no reaction
  • Carbylamine test

    1∘ amines+CHCl3​+KOH→isocyanide (foul smell)

Diazonium salts

  • ArNH2​NaNO2​, HCl, 0–5∘C​ArN2+​Cl−
  • Sandmeyer (CuX, CuCN); Gattermann (Cu/HX); H3​PO2​→ArH; coupling with phenol→azo dye

Cyanides, isocyanides and nitro compounds

  • RX+KCN→RCN;RX+AgCN→RNC;ArNO2​Sn/HCl​ArNH2​
Carboxylic Acids and Their DerivativesBiomolecules